2026 NBA Opening Day Odds: Spreads, Lines, What To Know For All 3 Games

The new NBA season opens on Oct. 20, with two colossal matchups in the East and the game’s newest rivalry in the West.

Let’s check out the odds for opening night at DraftKings Sportsbook as of Aug. 11.

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2026 NBA OPENING DAY ODDS

Celtics @ Pistons

Spread: Pistons -2.5 
Moneyline: Pistons -125, Celtics +105
O/U: 225.5

WHAT TO KNOW: What will be the situation with Jalen Duren come opening night? The Pistons’ second-best player had an abysmal playoff run, and is now embroiled in a contract dispute with the franchise. Will he be on the court for Detroit?

76ers @ Knicks

Spread: Knicks -4.5
Moneyline: Knicks -162, 76ers +136
O/U: 229.5

WHAT TO KNOW: The King visits the champs. Or, will he already be living in New York? LeBron James is part of the 76ers, and we will get to see the NBA’s best team against (supposedly) the NBA’s next best team.

Thunder @ Spurs

Spread: Spurs -2.5
Moneyline: Spurs -125, Thunder +105
O/U: 229.5

WHAT TO KNOW: It’s quickly transformed into arguably the greatest current rivalry in the NBA. The Thunder won their first title at the conclusion of the 2024-25 season, and were favored all year long during 2025-26. But the Spurs had other plans, knocking off the defending champions in a contentious seven-game West finals this past season. Now, the West juggernauts tip off the 2026-27 season. Last season, OKC was not an underdog in a single game until Feb. 4 … at San Antonio. Now, the Thunder are an underdog on Night 1.